Alzheimer's is the most common form of dementia, a brain disorder that affects memory and thinking skills. Learn about the signs, causes, and treatments of Alzheimer's from the National Institute on Aging (NIA), a federal agency that supports research and education on aging. Alzheimer's disease (AD) is the most common cause of dementia, and involves a progressive degeneration of the cerebral cortex. Alzheimer's disease is the most common type of dementia. Dementia is a collective name for progressive degenerative brain syndromes which affect memory, thinking, behaviour and emotion. Alzheimer’s disease is a progressive form of dementia that affects memory, thinking, and behavior. Learn about the causes, symptoms, treatments, and more.