Eye - Conjunctiva : primary acquired melanosisSee also benign melanosis 11% of conjunctival melanocytic proliferations (Arch Pathol Lab Med 2010;134:1785) Called melanoma in situ by some, although cases without atypia don't progress (Mod Pathol 1991;4:253) Variable biologic behavior from benign to locally spreading to malignant Usually ages 40+ years, whites Presents as gradual appearance of golden brown pigmented lesion of bulbar conjunctiva May be associated with Addison disease May be ... Mucous membrane that covers, protects and lubricates the posterior surface of the eyelids (palpebral, also known as tarsal, conjunctiva ) and anterior surface of the globe (bulbar conjunctiva ) Chronic papillary conjunctivitis (tarsal conjunctiva ) Numerous goblet cells and papillary folds Chronic inflammatory cells (lymphoid follicles and plasma cells) Isolated islands of epithelium may form retention cysts that calcify Late changes are epithelial atrophy, keratinization and stromal scarring Tumor-like lesions and choristomas of the conjunctiva Cysts of the conjunctiva and caruncle ICD-10: H11.449 Epithelial conjunctival inclusion cyst Reactive, epithelial and degenerative conjunctival lesions Reactive epithelial hyperplasia of the conjunctiva Papillary and follicular conjunctivitis Pterygium and pinguecula Choristomas of the ...