Define endeavour . endeavour synonyms, endeavour pronunciation, endeavour translation, English dictionary definition of endeavour . n. & v. Chiefly British Variant of ... ENDEAVOR definition : 1. US spelling of endeavour 2. to try to do something: 3. an attempt to do something: . Learn more. Endeavour is a formal word for trying very hard to do something or an attempt to do something new or original. Learn how to use it as a verb or a noun, and see synonyms and examples from Collins Dictionary. Endeavour is a formal word for an attempt to do something, especially something new or difficult. Learn how to use it in sentences, synonyms, collocations and word origin.