Oral glycerol syrup is one of the formulations used to reduce brain edema, especially in acute settings. This article explores the use of oral glycerol syrup for brain edema, focusing on its mechanism of action, recommended dosage, clinical applications, and potential side effects. Glycerol is also a key ingredient in cough syrups , wound care products, and intravenous solutions. Due to its ability to retain moisture, it is commonly used in skincare formulations to prevent dryness and irritation. Metabolism Glycerol undergoes extensive metabolism principally in the liver and to a lesser extent in the kidneys. Glycerol is metabolised to glucose or glycogen or oxidised to carbon dioxide and water. Glycerol syrup, also known simply as glycerin or glycerine , is a versatile compound used in various medical, pharmaceutical, and personal care applications. Its unique properties make it an essential ingredient in many formulations, from cough syrups to skin care products.