Lactulose is used in the treatment of Constipation, Intestine preparation before any surgery, Hepatic encephalopathy. View Lactulose’s uses , side-effects, drug interactions, expert advice and user FAQs only on 1mg.com. Lactulose (oral): side effects, dosage, interactions, FAQs, reviews. Used for: constipation, constipation, acute, constipation, chronic, hepatic encephalopathy Lactulose is an oral solution for the treatment of constipation and portal-systemic encephalopathy, a brain problem. Know its uses , side effects & precautions. Standard preparation— Transfer accurately weighed quantities of USP Lactulose RS, USP Anhydrous Lactose RS, and USP Epilactose RS to a 10-mL volumetric flask, and dissolve in and dilute with a mixture of water and acetonitrile (1:1) to volume, to obtain a solution having known concentrations of 40 mg per mL, 4.8 mg per mL, and 3.2 mg per mL, respectively.