Define manipulate . manipulate synonyms, manipulate pronunciation, manipulate translation, English dictionary definition of manipulate . tr.v. ma·nip·u·lat·ed , ma·nip·u·lat·ing , ma·nip·u·lates 1. To move, arrange, operate, or control by the hands or another body part or by mechanical means,... MANIPULATING definition : 1. present participle of manipulate 2. to control something or someone to your advantage, often…. Learn more. Explore the term ' manipulate ,' its meanings, origins, and how it is used in various contexts. Understand its positive and negative connotations, as well as synonyms, antonyms, and related terms. manipulate (third-person singular simple present manipulates, present participle manipulating , simple past and past participle manipulated) (transitive) To move, arrange or operate something using the hands (transitive) To influence, manage, direct, control or tamper with something
