Geography of Missouri : Ten facts about the state of Missouri , information about Missouri 's history, demographics, economy, geography and climate Missouri is a constituent state of the U.S. It is bordered by Iowa to the north; Illinois, Kentucky, and Tennessee to the east; Arkansas to the south; and Oklahoma, Kansas, and Nebraska to the west. The state’s major cities are Kansas City in the west and St. Louis in the east. Its capital is Jefferson City. Missouri is a state in the Midwestern region of the United States. It was acquired from France as part of the Louisiana Purchase in 1803 and was admitted into the Union as the 24th state in 1821. Missouri , the Show Me State, was admitted to the United States in 1821 as part of the Missouri Compromise. Located on the Mississippi and Missouri Rivers, the state was an important hub of ...