Vitamin B6 ( pyridoxine ) overview for health professionals. Research health effects, dosing, sources, deficiency, side effects, and interactions here. Pyridoxine is a form of vitamin B6, a water-soluble vitamin and an important micronutrient required for the normal functioning of many biological systems in the body. Pyridoxine is not synthesized naturally in humans and people must obtain it from dietary intake. Pyridoxine is used as a supplement to compensate for natural deficiency and to treat nausea and vomiting in pregnancy. Pyridoxine is also used to prevent or reduce nerve damage associated with isoniazid, a drug used to treat ... Pyridoxine Hydrochloride is used to treat vitamin B6/ pyridoxine hydrochloride deficiency. Vitamin B6 deficiency is caused due to malabsorption, protein-energy undernutrition, certain drugs or alcoholism. Pyridoxine is a vitamin used for preventing and treating low levels of pyridoxine ( pyridoxine deficiency) and the tired blood (anemia) that may result. It is also used for heart disease; high cholesterol; reducing blood levels of homocysteine, a chemical that might be linked to heart disease; and helping clogged arteries stay open after a balloon procedure to unblock them (angioplasty).