SGOT is an enzyme found primarily in the liver but is also present in the heart, brain, kidneys, and muscles. The enzyme is also known as AST or aspartate aminotransferase. The presence of this enzyme in the blood indicates liver damage or damage to other tissues. What Is an SGOT Test? The SGOT test, which stands for Serum Glutamic-Oxaloacetic Transaminase test , measures the amount of aspartate aminotransferase (AST) enzyme in the blood. SGOT plays a vital role in amino acid metabolism, facilitating the transfer of amino groups. One of the most important ways to assess liver health is through the measurement of liver enzymes, specifically SGOT (Serum Glutamic-Oxaloacetic Transaminase) and SGPT (Serum Glutamic-Pyruvic Transaminase). Did you know that elevated levels of these enzymes are often the first signs of liver damage? SGPT test , or Serum Glutamic Pyruvic Transaminase, is a blood test that can be used to detect any liver problems. It is commonly used to measure the level of a specific enzyme called ALT (alanine aminotransferase), a specific enzyme that is released when the liver is damaged or inflamed.