Sitagliptin is a DPP-4 inhibitor used to treat type 2 diabetes by increasing insulin production and decreasing glucagon production. It has common and serious side effects, and is available as a generic or in fixed-dose combinations with metformin or simvastatin. 100 mg tablets are beige, round, biconvex, film coated tablets debossed with "12" on one side and "42" on the other side. 50 mg tablets are pale yellow, round, biconvex, film coated tablets ... Find out how sitagliptin treats type 2 diabetes , and how to take it. NHS medicines information on sitagliptin – what it's used for, side effects, dosage and who can take it. Sitagliptin M 50mg/500mg Tablet is a combination of two medicines that control high blood sugar levels in people with type 2 diabetes mellitus. This helps prevent serious complications of diabetes, such as kidney damage and blindness and may reduce your chances of having a heart attack or stroke.

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