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Tablets: 25 mg round, light yellow, film-coated, with SEARLE and 1001 debossed on one side and ALDACTONE and 25 on the other side. Tablets: 50 mg oval, light orange, scored, film-coated, with ... The recommended initial daily dose is 25 to 100 mg of ALDACTONE administered in either single or divided doses is recommended. Dosage can be titrated at two-week intervals. It is typically used for the treatment of High BP, Edema. Other than this, Aldactone 25 Tablet has some other therapeutic uses, which have been discussed ahead. The optimal dosage of Aldactone 25 Tablet is largely dependent on the individual's body weight, medical history, gender and age. Aldactone 25 tablet is a diuretic medication , also known as a "water pill," with spironolactone as its active ingredient. It is primarily used to treat fluid retention (oedema) that can result from conditions such as congestive heart failure, liver cirrhosis, and certain kidney disorders.