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Bioavailability is the fraction of a drug or nutrient that reaches the systemic circulation. Learn how to measure bioavailability using area under the curve (AUC) and how it varies by route of administration, formulation and individual factors. Abstract Bioavailability, the degree and rate at which a substance is absorbed into the bloodstream and becomes available to its target site of action, is a critical factor in the efectiveness of medications and the utilization of nutrients. This article provides an overview of bioavailability, exploring the factors that influence it, including the route of administration, chemical characteristics of the substance, and individual variations in metabolism. The route of administration plays a ... Pharmaceutical Bioavailability and Bioequivalence Learn about Bioavailability, Bioequivalents, Therapeutic equivalents, In vitro Dissolution, Suprabioavailability, Therapeutic Equivalents, Technical Aspects and Acceptance ranges. Bioavailability is the amount to administrated drug that is used by the body. It is only possible to get the therapeutic effects of any drug when the drug can be absorbed by the body, so bioavailability is the key to making an enhancement that delivers proven benefits.