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Learn about the process of blood coagulation or clotting , the factors involved, the pathways and the disorders. Find out how platelets, fibrin and clotting factors work together to prevent bleeding and form a clot. Blood is a necessary component of the human body, and the loss of this fluid may be life-threatening. Blood is generated via hematopoiesis and ultimately becomes the delivery method for oxygen to the tissues and cells. The human body protects against loss of blood through the clotting mechanism. Vascular mechanisms, platelets, coagulation factors, prostaglandins, enzymes, and proteins are the contributors to the clotting mechanism which act together to form clots and stop a loss of blood ... Learn about blood clotting , a process that prevents excessive bleeding, and its complications, such as DVT and PE. Find out the risk factors, symptoms, and treatments of blood clots, and how to prevent them. Learn how blood clotting , or coagulation, reduces bleeding when we are injured. Find out how platelets, clotting factors and fibrin work together to form a clot and heal the wound.