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COAGULATION definition: 1. the process by which blood changes into a solid state to form a solid seal 2. the process by…. Learn more. “Platelets are minute fragments of blood cells that help in the formation of clots in the body to stop bleeding.” Any damage in the blood vessels sends signals to the platelets. The platelets rush to the site of damage and form clots to repair the damage. The activated platelets stick together to form a platelet plug which in turn activates the coagulation factor. Vitamin K is beneficial for the proper functioning of the coagulation factor. Let us have an overview of platelets and ... The classic coagulation cascade model of intrinsic and extrinsic coagulation pathways, i.e. contact activation pathway and tissue factor pathway, has been widely modified. The cascade can be categorized as follows: 1) initiation by tissue factor ... Key Points The coagulation cascade is a series of reactions, which is classically divided into three pathways: the contact (also known as the intrinsic) pathway, the tissue factor (also known as the extrinsic pathway), and the common pathway. The intrinsic pathway occurs when negatively charged molecule contact causes a cascade of factors that produce factor X. The extrinsic pathway occurs when tissue damage causes the release of tissue factor, creating a smaller cascade that produces factor ...
