Creatine is involved in making energy for muscles. About 95% of it is found in skeletal muscle. The majority of sports supplements in the US contain creatine . People who have lower creatine ... What is creatine? Creatine is a substance found naturally in muscle cells . It helps your muscles produce energy during heavy lifting or high intensity exercise. Creatine monohydrate is a popular supplement primarily taken to enhance muscle strength and power. However, it may provide other health benefits. Creatine itself can be phosphorylated by creatine kinase to form phosphocreatine, which is used as an energy buffer in skeletal muscles and the brain. A cyclic form of creatine , called creatinine, exists in equilibrium with its tautomer and with creatine .
