Glycolysis is the first step in the breakdown of glucose to extract energy for cellular metabolism. Glycolysis consists of an energy-requiring phase followed by an energy-releasing phase. Glycolysis , where the simple sugar glucose is broken down, occurs in the cytosol. Pyruvate, the product from glycolysis , is transformed into acetyl CoA in the mitochondria for the next step. Let's explore the process of glycolysis , the first phase of cellular respiration. Learn how this process breaks down glucose into two 3-carbon compounds, using two ATPs in the investment phase and generating a net of two ATPs in the payoff phase. The Krebs cycle occurs in the mitochondrial matrix, where pyruvate is turned into acetyl-CoA, which then goes through a series of reactions, producing ATP, NADH, and FADH2.

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