Guaifenesin is an expectorant that thins mucus and helps clear airways. Learn about its indications, contraindications, side effects, warnings, and brand names in India and internationally. Description Guaifenesin is used to help clear mucus or phlegm (pronounced flem) from the chest when you have congestion from a cold or flu. It works by thinning the mucus or phlegm in the lungs. This medicine is available both over-the-counter (OTC) and with your doctor's prescription. Do not give any over-the-counter (OTC) cough and cold medicine to a baby or child under 4 years of age. Using these medicines in very young children might cause serious or possibly life-threatening side effects . Guaifenesin tablet uses include treating cough and mucus buildup. Check dosage guidelines and tablet side effects to ensure safe, effective use. Cough Guaifenesin is used as an expectorant in the symptomatic management of coughs associated with the common cold, bronchitis, laryngitis, pharyngitis, pertussis, influenza, and measles, and coughs provoked by chronic paranasal sinusitis. While there is clinical evidence that guaifenesin is an effective expectorant (i.e., increasing expectorated sputum volume over the first 4-6 days of a productive cough, decreasing sputum viscosity and difficulty in expectoration, and improving associated ...