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Those infected with the HMPV virus could suffer from symptoms such as cough, fever, nasal congestion, and shortness of breath. According to the US CDC, clinical symptoms of HMPV infection may... HMPV is a respiratory virus that can cause cough, fever, and shortness of breath, but is generally less severe and contagious than COVID-19. Learn how HMPV and COVID-19 compare in terms of transmission, seasonality, affected populations, neurological impact, and mortality risk. Human metapneumovirus (HMPV) is garnering attention due to rising cases in China and advisories in Indian states like Karnataka and Maharashtra. While it's not a new virus, concerns are heightened because of limited research and public awareness. Here's everything you need to know about the virus. “While HMPV is not considered highly dangerous for the general public, it can cause severe respiratory complications like pneumonia and respiratory failure in vulnerable individuals,” Dr. Mittal explains.