Isordil ( Isosorbide Dinitrate ) may treat, side effects, dosage, drug interactions, warnings, patient labeling, reviews, and related medications including drug comparison and health resources. Enabling you to solve the toughest problems in life science. Complete your research with top quality products. Overview: Isosorbide dinitrate is a tablet taken to prevent chest pain from heart disease . It works by relaxing the blood vessels that deliver oxygen to the heart. Common side effects include... Isosorbide dinitrate is a medication for heart failure, angina, and esophageal spasms. It works by dilating blood vessels and is available as a generic drug in oral or sublingual forms.