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Not all cold medicines are the same. Read on for which active ingredients work best for the most common types of cold symptoms. Learn about the different types of OTC products that can help relieve cold symptoms, such as decongestants, antihistamines, pain relievers, and cough suppressants. Find out which medicines are suitable for different ages, conditions, and interactions, and how to use them safely. This article reviews the best cold medicines for a runny or stuffy nose, a sore throat, and for a wet or dry cough. It also looks at cold medicine interactions and how to treat cold symptoms at home. Learn about the best common cold medication options available over the counter and prescribed. Find out which treatments work best for you.