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A Notochord The notochord is a transient rod-like structure located at the developing midline, ventral to the neural tube and dorsal to the dorsal aorta. It is composed of a single column of large vacuolated cells surrounded by a thick BM. Studies of zebrafish mutants showed that this BM plays a fundamental role in notochord development and function (see for review Scott and Stemple, 2005). Transmission electron microscopy (TEM) reveals that the notochordal BM is composed of at least three ... The notochord is a flexible, rod-like structure seen in the embryos of all chordates. It provides all the necessary support and help in the development of the nervous system. In many animals, such as humans, the notochord is present only during the early stages of development and then gets replaced by the vertebral column (spine). The notochord is an embryonic midline structure common to all members of the phylum Chordata, providing both mechanical and signaling cues to the developing embryo. In vertebrates, the notochord ... The notochord (axial mesoderm, notochordal process, chorda dorsalis, Wirbelsäule) is the defining structure forming in all chordate embryos (taxonomic rank: phylum Chordata). It is an early forming midline structure in the trilaminar embryo mesoderm layer initially ventral to the ectoderm, then neural plate and finally neural tube. This is a transient embryonic anatomy structure, not existing in the adult, required for patterning the surrounding tissues. The patterning signal secreted by ...
