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Permite induces electrochemical abnormalities across the membranes of excitable cells, leading to sensory hyperexcitability, in coordination and prostration. Permite is rapidly metabolized in mammals by ester hydrolysis to inactive metabolites which are excreted primarily in the urine. The principal metabolites of Permite are detectable in the urine within hours of a whole body application of the cream to healthy volunteers or scabies patients. The highest levels of excretion are detectable ... Permite 5% Cream is a medicine that contains Permethrin. It is used for the treatment of scabies in adults and children aged from 2 months, and crab lice in adults. This medicine works by killing the mites, lice and their eggs thereby curing the infection. Permite Cream is used to treat scabies, a skin condition caused by mite infestations. It is also used to treat other conditions caused by similar skin parasites, providing relief from itching, irritation, and inflammation by killing the mites responsible for the infection. Permite is a pyrethroid cream that kills scabies and lice mites and eggs. Learn how to apply it, what are the common side effects, and who should avoid it.