probe (third-person singular simple present probes, present participle probing, simple past and past participle probed) (ambitransitive) To explore, investigate, question, test, or prove. quotations Probe definition: to search into or examine thoroughly; question closely.. See examples of PROBE used in a sentence. NextDon’t have an account? Sign up Revolutionize decision-making with Probe42 'for business' portal. Evaluate partners, track competitors, and collaborate seamlessly with comprehensive data insights.