Chromosomes are like small threads that are made up of DNA and proteins . DNA stands for deoxyribonucleic acid, which is the template on which all the structures of the body are created and maintained. There are several genes in each chromosome. A chromosome is a thread-like structure composed of a long molecule of DNA tightly coiled around proteins called histones. In eukaryotic cells, such as those in plants and animals, chromosomes are located inside the nucleus. They are the carriers of the genetic information required for a cell's growth, survival, and reproduction. Chromosomes are thin, thread like structures present in the nucleus and visible during all division. Each chromosome is made up of DNA (deoxyribonucleic acid) and proteins. What Are Chromosomes Made Of? At its core, a chromosome is made up of DNA , short for deoxyribonucleic acid. This DNA is coiled around protein structures called histones, much like thread wound around a spool. The resulting structure is known as chromatin.