Non-HDL cholesterol is a measure of all the “bad” types of cholesterol in your blood , including LDL, triglycerides, VLDL, and IDL, and is calculated by subtracting your HDL (“good”) cholesterol... Hidden in plain sight is a more powerful marker: non-HDL cholesterol (non-HDL-C) —a measure that captures all the cholesterol carried by atherogenic, plaque-building particles, not just LDL. Non-HDL cholesterol is essentially the total of all the “bad” cholesterols in your blood. It includes low-density lipoprotein (LDL), very-low-density lipoprotein (VLDL), intermediate-density lipoprotein (IDL), and lipoprotein (a) – all the particles that can contribute to plaque buildup in arteries.