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Learn about the omentum, including its structure and function, plus why it is important in metastatic malignancies, such as ovarian cancer. The omentum appears to be a primary site of B-lymphocyte development [19, 20]. In experimental animals, the omentum is a source of unique B-lymphocytes that demonstrate specific surface markers. These B-lymphocytes are predominantly CD5+ (Lyl+), and are common in not only the omentum but also the peritoneum. Understanding Omentum in Human Anatomy The omentum is a complex and multifaceted structure within the human body, playing a crucial role in various physiological processes and pathological conditions. This article aims to provide a comprehensive overview of the omentum, exploring its anatomy, functions, and clinical significance. What is Omentum? Greater omentum The greater omentum is part of the dorsal mesentery, is a large apron-like fold of peritoneum with a free lower border that attaches to the greater curvature of the stomach and the first part of the duodenum. The greater omentum is the longest peritoneal fold, it drapes over the transverse colon and coils of the jejunum and ileum like a “fatty apron”. The greater omentum is a double sheet that folds back on itself, giving it a total of four layers. Hanging behind the ...